For veterinary use only. Administer as directed by a licensed veterinarian.
Oriheal Vetosera Serratiopeptidase Proteolytic Enzyme Tablet for Dogs & Cats (10mg / 40mg)
Oriheal Vetosera is a veterinary tablet containing Serratiopeptidase (also known as Serrapeptase), a proteolytic enzyme originally isolated from the bacterium Serratia marcescens found in the gut of the Japanese silkworm (Bombyx mori), manufactured by Oriheal Lifesciences. Available in 10mg and 40mg strengths for weight-based dosing. Serratiopeptidase has anti-inflammatory, analgesic, and fibrinolytic properties and is used in veterinary practice for managing inflammation, oedema, and pain in dogs and cats, particularly in post-surgical recovery, musculoskeletal conditions, and non-healing wounds.
Composition (per tablet)
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Serratiopeptidase — 10mg (proteolytic enzyme) — Variant 1
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Serratiopeptidase — 40mg (proteolytic enzyme) — Variant 2
Mechanism of Action
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Proteolytic (fibrinolytic) activity: Serratiopeptidase hydrolyses and degrades fibrin, bradykinin, and other inflammatory mediator proteins at sites of inflammation — directly breaks down inflammatory exudate and reduces oedema
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Anti-inflammatory: Inhibits prostaglandin synthesis and reduces bradykinin levels at inflamed tissues — reduces pain and vascular permeability without the GI side effects associated with NSAIDs
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Fibrinolytic: Degrades fibrin deposits in post-surgical sites and non-healing wounds — improves local circulation, reduces scar tissue formation, and promotes wound healing
- Enhances drug penetration at inflamed sites by degrading fibrin barriers — useful as adjunct to antibiotic therapy in abscess management
Therapeutic Class
- Veterinary proteolytic enzyme (anti-inflammatory, analgesic, fibrinolytic) tablet for dogs and cats
Key Benefits
- Anti-inflammatory and analgesic without NSAID-associated GI or renal risks — suitable as adjunct or alternative in NSAID-sensitive animals
- Fibrinolytic action — degrades fibrin, reduces post-surgical oedema and scar tissue formation, promotes wound healing
- Two strength variants (10mg and 40mg) — enables accurate weight-based dosing for small and large dogs and cats
- Enhances antibiotic penetration at abscess and infected wound sites via fibrin barrier degradation
Indications
- Post-surgical oedema, pain, and swelling management
- Acute and chronic musculoskeletal inflammation — osteoarthritis, joint disorders, soft tissue injuries
- Non-healing wounds, abscesses, and tissue fibrosis
- Trauma-related oedema and haematoma resolution
- Adjunct to antibiotic therapy in abscess management
- Chronic inflammatory conditions where NSAID use is limited or contraindicated
Directions for Use
- Administer orally as directed by a licensed veterinarian
- Administer on an empty stomach where possible for optimal enzyme absorption
- Dosage determined by species, body weight, and condition — refer to veterinary prescription or label
Safety Information
- For veterinary use only; administer under licensed veterinary supervision
- Generally well tolerated; monitor for GI signs (nausea, loose stools) in sensitive animals
- Use with caution in animals with known clotting disorders — fibrinolytic activity may affect haemostasis
- Keep out of reach of children; store in a cool, dry place away from direct sunlight