Oriheal Pet Paltra Tramadol Hydrochloride 100mg/5ml Opioid Analgesic Oral Solution for Dogs & Cats | Moderate to Severe Pain, Post-Surgical & Visceral Pain | 60ml Veterinary Prescription

Prescription Required — For veterinary use only. Administer strictly under the supervision of a licensed veterinarian.

Oriheal Pet Paltra Tramadol Hydrochloride 100mg/5ml Opioid Analgesic Oral Solution for Dogs & Cats (60ml)

Oriheal Pet Paltra is a veterinary prescription palatable oral solution containing Tramadol Hydrochloride 100mg per 5ml, manufactured by Oriheal Lifesciences. Tramadol is a centrally-acting synthetic opioid analgesic that provides effective relief from moderate to severe pain in dogs and cats. Its dual mechanism — mu opioid receptor agonism and monoamine reuptake inhibition — makes it particularly effective for visceral pain (gastric, pancreatic) and post-surgical pain, and provides an analgesic option when NSAIDs are contraindicated or not tolerated.

Composition (per 5ml)

• Tramadol Hydrochloride — 100mg (centrally-acting synthetic opioid analgesic)
• Palatable oral solution base — q.s. to 60ml

Mechanism of Action

• Mu opioid receptor agonism: Tramadol binds to μ-opioid receptors in the CNS — inhibits ascending pain transmission and modulates descending pain inhibitory pathways, producing central analgesia
• Monoamine reuptake inhibition: Tramadol inhibits reuptake of serotonin (5-HT) and noradrenaline (NA) in spinal cord synapses — enhances descending inhibitory pain control; this non-opioid mechanism provides additional analgesic effect and contributes to visceral pain control
• Dual mechanism provides broader analgesic coverage than pure opioids for certain pain types, particularly visceral and neuropathic components

Therapeutic Class

• Veterinary centrally-acting synthetic opioid analgesic prescription oral solution for dogs and cats — moderate to severe pain management

Key Benefits

• Dual analgesic mechanism (mu opioid agonism + serotonin/noradrenaline reuptake inhibition) — effective for moderate to severe somatic and visceral pain
• Analgesic option when NSAIDs are contraindicated — renal disease, GI ulceration, concurrent corticosteroid use, or NSAID intolerance
• Palatable oral solution — accurate ml-based dosing; easier administration compliance vs. tablets
• Effective for visceral pain types (gastric, pancreatic) where NSAIDs have limited efficacy

Indications

• Moderate to severe acute pain in dogs and cats
• Post-surgical and perioperative pain management
• Visceral pain — gastric, pancreatic, and abdominal pain
• Chronic pain management in dogs and cats where NSAIDs are contraindicated or not tolerated
• Cancer-related pain as part of multimodal analgesic protocol
• Neuropathic pain components as adjunct analgesic

Directions for Use

• Administer orally as directed by a licensed veterinarian
• Measure dose accurately using an oral syringe — dosage determined by species, body weight, pain severity, and clinical condition; refer to veterinary prescription
• May be administered with or without food
• Do not exceed the prescribed dose or frequency

Safety Information

• Prescription medicine — for veterinary use only; administer under licensed veterinary supervision
• Cats — use with caution: Cats metabolise tramadol differently from dogs; feline-specific dosing is required; tramadol may cause dysphoria, mydriasis, or excessive vocalisation in cats — monitor closely and report to veterinarian
• Do not use concurrently with MAO inhibitors, SSRIs, tricyclic antidepressants, or serotonergic drugs — risk of serotonin syndrome
• Use with caution in animals with seizure history — tramadol lowers the seizure threshold
• Do not use in animals with severe hepatic impairment — tramadol is extensively hepatically metabolised
• Monitor for sedation, respiratory depression, vomiting, and constipation — common opioid-class adverse effects
• Keep out of reach of children; store in a cool, dry place away from direct sunlight; keep bottle tightly closed