Prescription Required — For veterinary use only. Administer strictly under the supervision of a licensed veterinarian.
Oriheal Palapan D Pantoprazole & Domperidone Tablet for Dogs & Cats
Oriheal Palapan D is a veterinary combination tablet containing Pantoprazole (proton pump inhibitor — PPI) and Domperidone (dopamine D2 antagonist prokinetic), manufactured by Oriheal Lifesciences. Available in three strength combinations, Palapan D is indicated for the management of acid reflux, gastritis, gastroesophageal reflux disease (GERD), gastric hypersecretion, gastric ulcers, and vomiting associated with impaired gastric motility in dogs and cats.
Variants Available
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Palapan D 10: Pantoprazole 10mg + Domperidone 2.5mg per tablet
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Palapan D 20: Pantoprazole 20mg + Domperidone 5mg per tablet
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Palapan D 40: Pantoprazole 40mg + Domperidone 10mg per tablet
Mechanism of Action
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Pantoprazole (PPI): Irreversibly inhibits the gastric H+/K+ ATPase (proton pump) — reduces gastric acid secretion; treats acid reflux, GERD, gastric ulcers, and gastric hypersecretion
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Domperidone (Prokinetic): Dopamine D2 receptor antagonist — enhances gastric motility and gastric emptying; reduces nausea and vomiting associated with gastric stasis
Therapeutic Class
- Veterinary PPI + prokinetic combination prescription tablet — proton pump inhibitor (Pantoprazole) and dopamine D2 antagonist (Domperidone) for gastric acid and motility management in dogs and cats
Key Benefits
- Pantoprazole — potent and sustained reduction of gastric acid secretion via proton pump inhibition
- Domperidone — improves gastric motility and gastric emptying; reduces nausea and vomiting
- Combination approach — simultaneously manages gastric acid and gastric motility disorders
- Available in 3 strength combinations for veterinarian-guided dose selection based on species and body weight
Indications
- Acid reflux and gastroesophageal reflux disease (GERD) in dogs and cats
- Gastritis and gastric hypersecretion
- Gastric and duodenal ulcers
- Vomiting associated with gastric stasis or impaired gastric motility
- Nausea and vomiting management as adjunct prokinetic therapy
- Supportive gastric protection during NSAID or corticosteroid therapy
Directions for Use
- Administer orally as directed by a licensed veterinarian
- Ideally give on an empty stomach 30–60 minutes before feeding for optimal Pantoprazole absorption
- Dosage, strength selection, and duration determined by the prescribing veterinarian based on species, body weight, and diagnosis
Safety Information
- Prescription medicine — for veterinary use only; administer under licensed veterinary supervision
- Do not use without a valid veterinary prescription
- Use with caution in animals with hepatic impairment — both Pantoprazole and Domperidone are hepatically metabolised
- Long-term PPI use may affect magnesium absorption and gut microbiome — monitor on extended therapy
- Keep out of reach of children; store in a cool, dry place away from direct sunlight