Prescription Required (Rx) — For veterinary use only. Administer strictly under the supervision of a licensed veterinarian.
OriHeal Pimotone Plus-5 Pimobendan & Benazepril Easy Chews Tablet for Dogs & Cats (Pack of 10)
OriHeal Pimotone Plus-5 is a veterinary cardiac prescription tablet combining Pimobendan and Benazepril Hydrochloride in an easy chews formulation, manufactured by OriHeal Lifesciences. Pimotone Plus-5 combines the inotropic and vasodilatory action of Pimobendan (a calcium sensitiser and PDE-3 inhibitor) with the ACE-inhibiting action of Benazepril, providing dual-mechanism cardiac support for the management of congestive heart failure (CHF), dilated cardiomyopathy (DCM), and systemic hypertension in dogs and cats.
Composition (per tablet)
-
Pimobendan — 5mg (calcium sensitiser and phosphodiesterase-3 (PDE-3) inhibitor — positive inotrope and vasodilator)
-
Benazepril Hydrochloride (ACE inhibitor — reduces cardiac afterload and preload; confirm exact mg strength from product label)
- Easy chews palatable base — for voluntary oral administration
Note: Confirm exact Benazepril strength (mg) from the product label and update accordingly.
Mechanism of Action
- Pimobendan — increases myocardial contractility (positive inotrope) via calcium sensitisation; reduces cardiac preload and afterload via PDE-3 inhibition and vasodilation
- Benazepril — ACE inhibitor; blocks conversion of angiotensin I to angiotensin II, reducing systemic vascular resistance, cardiac afterload, and aldosterone-mediated fluid retention
- Dual action — improves cardiac output while reducing the workload on the failing heart
Therapeutic Class
- Veterinary cardiac prescription combination tablet — positive inotrope (calcium sensitiser/PDE-3 inhibitor) + ACE inhibitor for dogs and cats
Key Benefits
- Dual-mechanism cardiac support — Pimobendan (inotropic/vasodilatory) + Benazepril (ACE inhibition) in a single tablet
- Improves cardiac output and reduces cardiac workload in heart failure
- Reduces systemic hypertension via ACE inhibition
- Easy chews formulation — palatable; supports voluntary dosing compliance in dogs and cats
- Supports quality of life and exercise tolerance in pets with cardiac disease
Indications
- Congestive heart failure (CHF) in dogs and cats
- Dilated cardiomyopathy (DCM) in dogs
- Myxomatous mitral valve disease (MMVD) — as indicated by the prescribing veterinarian
- Systemic hypertension in dogs and cats
- Cardiac disease management as part of a veterinary cardiac treatment protocol
Directions for Use
- Administer orally as directed by a licensed veterinarian — easy chews can be given voluntarily or with food
- Dosage based on body weight and cardiac diagnosis; determined by the prescribing veterinarian
- Do not discontinue without veterinary guidance — abrupt withdrawal may worsen cardiac status
Safety Information
- Prescription medicine (Rx) — for veterinary use only; administer under licensed veterinary supervision
- Do not use without a valid veterinary prescription
- Use with caution in animals with renal impairment — Benazepril undergoes hepatic and renal elimination; monitor renal function during long-term use
- Monitor blood pressure, renal parameters, and electrolytes during therapy
- Do not use concurrently with other ACE inhibitors or NSAIDs without veterinary guidance
- Keep out of reach of children; store in a cool, dry place away from direct sunlight