Prescription Required — For veterinary use only. Administer strictly under the supervision of a licensed veterinarian.
Oriheal Petzipine Mirtazapine 15mg Appetite Stimulant & Antiemetic Tablet for Dogs & Cats
Oriheal Petzipine is a veterinary prescription tablet containing Mirtazapine 15mg, manufactured by Oriheal Lifesciences. Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA) used in veterinary medicine as an appetite stimulant, antiemetic, and behavioural support agent in dogs and cats. Petzipine is indicated for the management of anorexia, reduced appetite, nausea, vomiting, weight loss, and behavioural changes associated with chronic illness, systemic disease, or recovery.
Composition
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Mirtazapine — 15mg per tablet (NaSSA — noradrenergic and specific serotonergic antidepressant; appetite stimulant and antiemetic)
Mechanism of Action
- Mirtazapine blocks central alpha-2 adrenergic receptors and histamine H1 receptors, increasing noradrenergic and serotonergic neurotransmission — resulting in appetite stimulation, antiemetic effects, and antidepressant action
- Anti-nausea effects are mediated via 5-HT3 receptor antagonism
Therapeutic Class
- Veterinary NaSSA — appetite stimulant, antiemetic, and antidepressant prescription tablet for dogs and cats
Key Benefits
- Stimulates appetite and promotes healthy food intake and weight gain in anorexic pets
- Reduces nausea and vomiting in pets with gastrointestinal or systemic illness
- Supports behavioural and emotional well-being in chronically ill or stressed pets
- Useful during recovery from illness, surgery, or prolonged medical treatment
- Effective for both acute and chronic appetite and nausea management
Indications
- Anorexia and reduced appetite in dogs and cats associated with chronic illness, systemic disease, CKD, or cancer
- Nausea and vomiting management (antiemetic use)
- Weight loss and nutritional support during illness or recovery
- Behavioural support in pets with chronic illness, stress, or depressive-like states
- Adjunct nutritional and emotional support during recovery from illness or medical treatment
Directions for Use
- Administer orally as directed by a licensed veterinarian
- Dosage and frequency depend on the pet’s species, body weight, and medical condition — cats typically require lower doses and less frequent administration than dogs; refer to veterinary prescription
- Can be given with or without food
Safety Information
- Prescription medicine — for veterinary use only; administer under licensed veterinary supervision
- Do not use without a valid veterinary prescription
- Use with caution in pets with renal or hepatic impairment — dose adjustment may be required
- Do not use concurrently with MAO inhibitors or serotonergic drugs without veterinary guidance — risk of serotonin syndrome
- Monitor for sedation, agitation, or vocalization particularly in cats during initial dosing
- Keep out of reach of children; store in a cool, dry place away from direct sunlight