For external veterinary use only. Apply topically as directed by a licensed veterinarian. Avoid contact with eyes and mucous membranes. Do not allow pet to lick application site immediately after use. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
Vivaldis Ceravet Lotion for Dogs & Cats (100ml)
Vivaldis Ceravet Lotion is a veterinary topical lotion formulated for dogs and cats with compromised skin barrier function. As the name indicates, Ceravet is ceramide-based — delivering ceramides and skin barrier-supportive lipids directly to the skin surface to replenish the ceramide-depleted stratum corneum, restore epidermal lipid barrier integrity, reduce transepidermal water loss (TEWL), and soothe dry, flaky, inflamed, and pruritic skin. Suitable for daily use as part of a veterinary-managed skin barrier repair and atopic dermatitis supportive care programme. Confirm complete active ingredient composition and concentrations from the Vivaldis Ceravet Lotion product label or package insert.
Composition (confirm from product label)
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Ceramides — confirm concentration from product label: Ceramides are the primary sphingolipid components of the stratum corneum (the outermost layer of the epidermis); they form approximately 50% of the total lipid content of the stratum corneum and are the structural backbone of the lamellar lipid bilayer — the organised lipid membrane that seals the skin barrier and controls transepidermal water loss (TEWL); ceramide deficiency in the stratum corneum is the primary pathophysiological defect in canine atopic dermatitis (CAD) and feline atopic skin syndrome (FASS), caused by upregulated ceramidase enzyme activity in atopic skin that cleaves and degrades ceramides faster than they can be replenished; ceramide-depleted stratum corneum has a disrupted lamellar lipid bilayer, resulting in increased TEWL (leading to skin dryness and dehydration), impaired skin barrier function (allowing enhanced penetration of environmental allergens, irritants, and microorganisms), and heightened skin immune sensitisation and pruritic signalling; topical Ceravet ceramide replenishment restores stratum corneum ceramide content, re-establishes lamellar lipid bilayer structure and integrity, reduces TEWL, and improves skin barrier function — reducing allergen penetration, skin sensitisation, and pruritus
- Additional skin barrier-supportive lipids and emollients — may include cholesterol, free fatty acids (linoleic acid, palmitic acid), phytosphingosine, or other stratum corneum lipid components; confirm from Vivaldis Ceravet Lotion product label; the natural stratum corneum lamellar lipid bilayer has an approximately equimolar ratio of ceramides, cholesterol, and free fatty acids — topical products that restore all three lipid classes provide more complete barrier repair than ceramide alone
- Lotion base and excipients — confirm from Vivaldis Ceravet Lotion product label
Therapeutic Class
- Veterinary topical ceramide-based skin barrier repair lotion — compromised skin barrier restoration, TEWL reduction, atopic dermatitis adjunctive skin care for dogs and cats
Key Benefits
- Skin barrier integrity restoration — ceramides replenish ceramide-depleted stratum corneum, restoring the lamellar lipid bilayer and reducing transepidermal water loss (TEWL); directly addresses the primary pathophysiological defect of canine and feline atopic dermatitis
- Reduced allergen and irritant penetration — restored skin barrier reduces transcutaneous penetration of environmental allergens (house dust mites, pollens, grass, mould spores), chemical irritants, and microorganisms into the epidermis
- Reduced secondary infection risk — improved skin barrier reduces transcutaneous penetration of Staphylococcus pseudintermedius and Malassezia yeast — the primary secondary pathogens of atopic dermatitis skin flares in dogs and cats
- Pruritus (itch) reduction — improved barrier function reduces allergen sensitisation and inflammatory mediator production, reducing pruritic signalling; skin hydration reduces itch-mediating neuropeptide release from dry, dehydrated keratinocytes
- Skin hydration and soothing — emollient lotion base and ceramide-restored barrier reduce skin dryness, flakiness, scaling, and irritation associated with compromised skin barrier function
- Daily maintenance skin care — suitable for regular topical application as part of a long-term skin barrier maintenance programme in dogs and cats with chronic atopic or barrier-compromised skin disease
Indications
- Compromised skin barrier function in dogs and cats — primary indication; ceramide-depleted stratum corneum with increased TEWL, dryness, and enhanced allergen penetration
- Canine atopic dermatitis (CAD) — adjunctive topical skin barrier repair alongside systemic atopic dermatitis management (Cyclosporin/Atosporin, Apoquel/oclacitinib, Cytopoint/lokivetmab, allergen-specific immunotherapy)
- Feline atopic skin syndrome (FASS) — topical ceramide skin barrier repair in cats
- Allergic skin disease and environmental allergen hypersensitivity in dogs and cats with skin barrier compromise
- Dry, flaky, scaly skin (xerosis) — generalised or localised skin dryness and barrier compromise
- Chronic pruritus and recurrent skin flares with concurrent skin barrier deficiency
- Post-bathing or post-treatment skin barrier maintenance — application after medicated shampoos (benzoyl peroxide, chlorhexidine, miconazole) to restore barrier lipids removed during shampooing
- Skin barrier support during and after corticosteroid therapy — corticosteroids reduce ceramide synthesis in skin; topical Ceravet may help restore ceramide content during and after steroid use
Directions for Use
- For external use only — apply topically to affected skin areas as directed by a licensed veterinarian
- Part the fur to expose the skin surface at the affected area before application
- Apply a thin, even layer of lotion to the affected area and massage gently into the skin
- Do not allow pet to lick the application site immediately after use; allow lotion to absorb before contact
- Avoid contact with eyes and mucous membranes; if contact occurs, flush with water
- Application frequency and duration — confirm from Vivaldis Ceravet Lotion product label or veterinary recommendation; typically applied once or twice daily to affected areas or as a post-bathing skin barrier restore
Safety Information
- For external veterinary use only — do not administer orally
- Ceravet Lotion is a topical skin barrier supportive product — it does not replace veterinary-prescribed antipruritic or immunomodulatory treatments where these are indicated for underlying atopic dermatitis
- Confirm suitability for pregnant, lactating, and breeding animals from product label or veterinarian before use
- Discontinue if any adverse skin reaction (increased irritation, redness, or worsening of skin condition) is observed; consult a veterinarian
- Keep out of reach of children; store in a cool, dry place away from direct sunlight; keep cap tightly closed after use