Oriheal Ziflunar Fluralaner Soft Chew for Dogs | Isoxazoline | Kills Ticks, Fleas, Mites, Sarcoptic Mange & Demodex | 3 Months Protection | 250mg, 500mg & 1000mg

Oriheal Ziflunar Fluralaner Oral Soft Chew for Dogs (250mg, 500mg & 1000mg)

Oriheal Ziflunar is a systemic oral ectoparasiticide soft chew for dogs containing Fluralaner, an isoxazoline-class acaricide and insecticide. A single palatable soft chew delivers immediate and sustained systemic killing activity against the most clinically important fleas, ticks, and mites, with a duration of action of up to 3 months — substantially reducing the dosing frequency of conventional monthly products.

Fluralaner acts after parasites attach and begin feeding, by blocking ligand-gated chloride channels (GABA and glutamate-gated) in the parasite nervous system, causing paralysis and death. It provides a single-dose treatment option for sarcoptic mange, demodicosis, and otoacariasis, and is active against fipronil-resistant flea strains. Safe for use in breeding, pregnant, and lactating bitches.

Active Ingredient

• Fluralaner — isoxazoline acaricide and insecticide; systemic, feed-activated; blocks GABA and glutamate-gated chloride channels in parasite nervous system

Presentations & Dosing (By Body Weight)

• Small dogs 4.5–10 kg — 250mg fluralaner per chew (1 chew)
• Medium dogs 10–20 kg — 500mg fluralaner per chew (1 chew)
• Large dogs 20–40 kg — 1000mg fluralaner per chew (1 chew)
• Extra-large dogs 40–56 kg — 1400mg fluralaner per chew (1 chew)
• Dogs above 56 kg — use combination of chews matching body weight, or as directed by veterinarian
• Minimum dose: ≥25 mg/kg body weight

Key Benefits

• Single oral soft chew — 3 months protection against ticks and fleas
• Fast onset: flea kill from approximately 1 hour; tick kill within hours of attachment
• Systemic, feed-activated action — parasites killed on contact with blood after feeding
• Single-dose treatment for sarcoptic mange (Sarcoptes scabiei), demodicosis (Demodex spp.), and ear mites (otoacariasis)
• Effective against fipronil-resistant flea strains
• Safe for breeding, pregnant, and lactating bitches
• Palatable soft chew — easy to administer with or around feeding

Indications

• Tick infestation in dogs (all common species including Rhipicephalus, Ixodes, Haemaphysalis)
• Flea infestation including fipronil-resistant strains (Ctenocephalides canis, C. felis)
• Sarcoptic mange (Sarcoptes scabiei) in dogs — single dose
• Demodicosis (Demodex canis) in dogs — single dose
• Otoacariasis (ear mite infestation, Otodectes cynotis) in dogs — single dose
• Prevention of tick-borne and flea-borne disease risk through fast kill

Directions for Use

• Select the correct chew strength based on the dog’s body weight
• Administer one chew orally with or around feeding for best absorption
• Do not break or divide the chew
• Repeat every 3 months for continuous tick and flea protection
• For mange and Demodex, administer as directed by a veterinarian

Safety Information

• For use in dogs only
• Not for use in puppies under 8 weeks of age or dogs under 2 kg
• Safe for use in breeding, pregnant, and lactating bitches — confirm with veterinarian
• Use with caution in dogs with a history of neurological disorders (isoxazoline class effect)
• Keep out of reach of children
• Store in a cool, dry place away from direct sunlight