Oriheal Palacef-TZ Cefoperazone + Sulbactam & Metronidazole Veterinary Injection for Dogs, Cats & Livestock | Bacterial & Protozoal Infection, Respiratory, GI & Urogenital | Veterinary Prescription

Prescription Required — For veterinary use only. Administer strictly under the supervision of a licensed veterinarian. Injectable medicine — for intravenous (IV) or intramuscular (IM) administration by a qualified veterinary professional only.

Important Notice: The exact active concentrations in Oriheal Palacef-TZ Injection are not confirmed on this product page. "Palacef-TZ" is presumed to indicate Cefoperazone + Sulbactam (Palacef) combined with Metronidazole or Tinidazole (TZ). Verify the complete composition and concentrations from the physical product label and update accordingly.

Oriheal Palacef-TZ Cefoperazone + Sulbactam & Metronidazole Veterinary Injection

Oriheal Palacef-TZ is a veterinary prescription combination antibiotic and antiprotozoal injectable formulation manufactured by Oriheal Lifesciences. It combines a third-generation cephalosporin (Cefoperazone) with a beta-lactamase inhibitor (Sulbactam) for broad-spectrum antibacterial coverage, and Metronidazole (or Tinidazole) for anaerobic bacterial and protozoal activity. This combination provides effective coverage against a wide range of Gram-positive, Gram-negative, anaerobic bacteria, and protozoal organisms, making it suitable for mixed and polymicrobial infections in companion animals and livestock. Available in two strengths: 562.5mg and 1.125g.

Composition (per vial — confirm from product label)

• 562.5mg variant:
  • Cefoperazone Sodium — (confirm mg from label) — third-generation cephalosporin antibiotic
  • Sulbactam Sodium — (confirm mg from label) — beta-lactamase inhibitor (protects Cefoperazone from resistant organisms)
  • Metronidazole / Tinidazole — (confirm active and mg from label) — anaerobic antibacterial and antiprotozoal
• 1.125g variant: Double-strength formulation (confirm from label)

Therapeutic Class

• Veterinary combination antibiotic (third-generation cephalosporin + beta-lactamase inhibitor) and antiprotozoal (nitroimidazole) prescription injection — broad-spectrum bacterial and protozoal infection management in companion animals and livestock

Key Benefits

• Cefoperazone — third-generation cephalosporin with broad Gram-positive and Gram-negative antibacterial spectrum, including Pseudomonas aeruginosa
• Sulbactam — beta-lactamase inhibitor that restores Cefoperazone activity against beta-lactamase-producing resistant organisms
• Metronidazole / Tinidazole — nitroimidazole antiprotozoal and anaerobic antibacterial; covers anaerobes and protozoal pathogens (Giardia, Trichomonas, Entamoeba) not covered by cephalosporins
• Combination provides polymicrobial and mixed anaerobic-aerobic infection coverage in one formulation
• Parenteral (IV/IM) delivery — rapid systemic therapeutic levels; preferred for severe or hospitalised infections

Indications

• Bacterial infections of the respiratory tract (pneumonia, bronchopneumonia)
• Gastrointestinal infections including anaerobic and protozoal GI disease
• Urogenital infections (UTI, pyelonephritis, metritis)
• Skin and soft tissue infections (pyoderma, wound infections, abscesses)
• Polymicrobial and mixed aerobic-anaerobic infections
• Post-surgical infection prevention and treatment
• Protozoal infections (Giardia, Trichomonas, anaerobic protozoal disease) — confirm from label active

Directions for Use

• Administer by intravenous (IV) or intramuscular (IM) injection as directed by a licensed veterinarian
• Reconstitute and prepare strictly per label instructions and veterinary protocol
• Dosage determined by species, body weight, infection severity, and variant strength — refer to veterinary prescription
• Complete the full prescribed antibiotic course; do not discontinue early even if clinical signs improve

Safety Information

• Prescription medicine — for veterinary use only; injectable administration by a licensed veterinary professional only
• Confirm beta-lactam hypersensitivity (penicillin/cephalosporin) before administration
• Metronidazole/Tinidazole — avoid in pregnant animals in early gestation; use with caution in animals with hepatic disease
• Do not use without confirmed indication — antibiotic stewardship applies; third-generation cephalosporins are critically important antibiotics (WHO classification)
• Keep out of reach of children; store as directed on label; use immediately after reconstitution