Prescription Required — For veterinary use only. Administer strictly under the supervision of a licensed veterinarian.
Important Notice: Active ingredients below are based on the product name (GP = Gentamicin + Prednisolone) and common Indian veterinary ophthalmic formulations. Verify all details from the physical product label before publishing.
Oriheal Opthovet GP Gentamicin & Prednisolone Ophthalmic Eye Drops for Dogs & Cats
Oriheal Opthovet GP is a veterinary prescription ophthalmic solution combining Gentamicin (aminoglycoside antibiotic) and Prednisolone (corticosteroid anti-inflammatory), manufactured by Oriheal Lifesciences. Opthovet GP is indicated for the treatment of bacterial ocular infections and inflammatory ocular conditions in dogs and cats, including conjunctivitis, keratitis, blepharitis, anterior uveitis, and mixed bacterial-inflammatory eye conditions requiring concurrent antibiotic and anti-inflammatory therapy.
Composition (to be confirmed from product label)
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Gentamicin — concentration % (confirm from label) — aminoglycoside antibiotic
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Prednisolone — concentration % (confirm from label) — corticosteroid anti-inflammatory
- Sterile ophthalmic vehicle base — q.s.
Mechanism of Action
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Gentamicin (aminoglycoside antibiotic): Binds irreversibly to the 30S ribosomal subunit of susceptible bacteria — causes misreading of mRNA and inhibits bacterial protein synthesis; bactericidal activity against gram-negative organisms (Pseudomonas aeruginosa, E. coli, Klebsiella) and gram-positive organisms (Staphylococcus spp.) commonly causing ocular infections
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Prednisolone (corticosteroid): Inhibits phospholipase A2 via glucocorticoid receptor-mediated lipocortin induction — suppresses prostaglandin, leukotriene, and cytokine-mediated ocular inflammation; reduces conjunctival and corneal oedema, hyperaemia, and vascular permeability
Therapeutic Class
- Veterinary ophthalmic aminoglycoside antibiotic + corticosteroid combination prescription eye drops for dogs and cats
Key Benefits
- Gentamicin — broad-spectrum aminoglycoside bactericidal coverage including Pseudomonas and Staphylococcus — key pathogens in canine and feline ocular infections
- Prednisolone — effective anti-inflammatory for rapid reduction of ocular redness, oedema, and discomfort
- Combination approach — simultaneously eliminates bacterial infection and controls associated ocular inflammation
- Sterile ophthalmic formulation — suitable for direct instillation into the eye
Indications
- Bacterial conjunctivitis in dogs and cats
- Bacterial and inflammatory keratitis
- Anterior uveitis and uveal inflammatory conditions
- Blepharitis — bacterial and inflammatory eyelid infections
- Mixed bacterial and inflammatory ocular conditions requiring combined antibiotic and corticosteroid therapy
Directions for Use
- Instil 1–2 drops into the affected eye(s) as directed by a licensed veterinarian
- Frequency and duration determined by the prescribing veterinarian based on species, diagnosis, and clinical response
- Gently clean ocular discharge from around the eye before instillation if present
- Do not touch the dropper tip to the eye, eyelid, or any surface — replace cap immediately after use to maintain sterility
Safety Information
- Prescription medicine — for veterinary use only; administer under licensed veterinary supervision
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Do not use if corneal ulceration is present or suspected — corticosteroid-containing ophthalmic drops are contraindicated in corneal ulcers; confirm corneal integrity (fluorescein stain test) before initiating treatment
- Prolonged corticosteroid ophthalmic use may increase intraocular pressure — monitor on extended therapy
- Use with caution in animals with suspected viral (herpetic) ocular infections — corticosteroids may exacerbate viral keratitis
- Gentamicin is potentially ototoxic if used in ears with ruptured tympanic membrane — ophthalmic use only
- Keep out of reach of children; store in a cool, dry place away from direct sunlight; discard after stated expiry