For animal use. Administer as directed by a veterinarian or as per label instructions. For external ear and superficial skin use only — do not instil into a ruptured or perforated ear drum.
Drools EarSoothe-TE Tris-EDTA & N-Acetylcysteine Sterile Ear Cleanser for Dogs & Cats (100ml)
Drools EarSoothe-TE is a sterile veterinary ear and superficial skin cleansing solution formulated with Tris-EDTA and N-Acetylcysteine (NAC) for the management of bacterial and fungal ear infections, otitis externa, and ear hygiene in dogs and cats. The dual-active combination provides biofilm disruption (Tris-EDTA), mucolytic action (NAC), and antioxidant protection of inner ear hair cells (NAC), making it effective for routine ear hygiene maintenance and as an adjunct to topical antimicrobial ear therapy. Also suitable for superficial skin cleansing in bacterial and fungal skin infections.
Composition (per ml — confirm concentrations from product label)
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Tris-EDTA (Tromethamine-EDTA) — chelating agent; disrupts the outer membrane of Gram-negative bacteria (including Pseudomonas aeruginosa) and fungal cell walls; breaks down and prevents bacterial and fungal biofilm formation; enhances penetration of topical antimicrobials into biofilm
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N-Acetylcysteine (NAC) — mucolytic agent (thins and dissolves thick ear discharge, mucus, and debris); antioxidant (protects inner ear hair cells from oxidative damage); also has independent antibiofilm activity
- Sterile aqueous vehicle — confirm from label
- Concentrations — confirm from physical Drools EarSoothe-TE product label
Therapeutic Class
- Veterinary sterile ear and superficial skin cleanser — Tris-EDTA + N-Acetylcysteine biofilm control, mucolytic, and antioxidant formula for dogs and cats
Key Benefits
- Tris-EDTA — disrupts Gram-negative bacterial outer membranes (particularly Pseudomonas aeruginosa, the most common cause of treatment-resistant otitis in dogs) and fungal cell walls; breaks down established biofilms and prevents new biofilm formation
- N-Acetylcysteine (mucolytic) — thins and dissolves thick, viscous ear discharge and mucus debris, improving cleanser penetration and facilitating debris removal
- N-Acetylcysteine (antioxidant) — scavenges free radicals; protects delicate inner ear hair cells from oxidative damage associated with chronic or severe otitis
- Synergistic biofilm control — Tris-EDTA + NAC combination disrupts biofilm structure, significantly enhancing the efficacy of any concurrently applied topical antibiotic or antifungal ear medication
- Reduces recurrence — biofilm disruption reduces bacterial and fungal reservoir that drives recurrent otitis externa
- Sterile formulation — suitable for use in ears with inflamed, sensitive, or compromised canal epithelium
Indications
- Bacterial otitis externa — including Pseudomonas aeruginosa and Staphylococcal infections
- Fungal otitis externa — Malassezia pachydermatis (yeast) ear infection
- Mixed bacterial-fungal otitis externa
- Biofilm-associated recurrent or treatment-resistant ear infections
- Routine ear hygiene and wax/debris removal maintenance
- Adjunct to topical antibiotic or antifungal ear medication (pre-treatment cleaning)
- Superficial bacterial or fungal skin infections — skin fold dermatitis, interdigital, and perianal cleansing
Directions for Use
- Gently instil solution into the ear canal as directed by a veterinarian
- Massage the base of the ear gently to distribute the solution and loosen debris
- Allow the animal to shake its head, then gently wipe the outer ear canal with a clean cotton ball or gauze — do not insert cotton buds into the ear canal
- For use as pre-treatment before topical antimicrobial ear medication: instil, massage, wipe, and allow to dry before applying ear drops
- Frequency of use as directed by a veterinarian (typically once or twice daily for active infection; reduce to weekly or biweekly for maintenance)
- Do not use if the ear drum is known or suspected to be ruptured or perforated
Safety Information
- For external ear and superficial skin use only — do not instil into ears with known or suspected tympanic membrane (ear drum) perforation
- If signs of pain, excessive head shaking, or deterioration are observed after use, discontinue and consult a veterinarian
- Keep out of reach of children; store in a cool, dry place away from direct sunlight; keep bottle tightly closed after use