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Brand / Manufacturer: Corise Healthcare Pvt. Ltd.
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Product Name: Corise Diarest O2 (Ofloxacin + Ornidazole) Tablet for Dogs (Pack of 10)
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Category / Class: Antibiotic / Antidiarrheal (gastrointestinal medication)
Composition & Mechanism
Each tablet contains:
| Active Ingredient | Strength | Action / Role |
|---|---|---|
| Ofloxacin | 200 mg | A fluoroquinolone antibiotic. Works by inhibiting bacterial DNA gyrase/topoisomerase, preventing bacteria from replicating or repairing their DNA. Useful especially for aerobic, Gram-positive, Gram-negative bacteria. |
| Ornidazole | 500 mg | A nitroimidazole class drug effective against anaerobic bacteria and certain protozoa. It interferes with DNA in susceptible organisms, leading to death of anaerobic pathogens. |
| Excipients / Others | q.s. (as needed) | To form the tablet matrix and facilitate absorption. |
The combination aims to cover both aerobic & anaerobic bacteria, as well as protozoal infections, especially in the gastrointestinal (GI) tract.
Indications / Uses
Corise Diarest O2 is indicated in dogs for:
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Mixed gastrointestinal infections (i.e. where both aerobic and anaerobic microbes may be present.
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Diarrhea (loose stool) with suspected bacterial / protozoal origin
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Bacterial & protozoal infections in GI tract (involving susceptible organisms)
Dosage & Administration
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The standard recommendation (in some sources) is for dogs up to 20 kg: 1 tablet, twice a day (BID).
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However, actual dosage should always be decided by a veterinarian based on weight, severity of disease, and other health parameters.
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Administer orally, with food (if possible) to reduce GI upset.
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Duration of therapy depends on the response and the specific diagnosis; never discontinue prematurely without veterinary advice.
Precautions, Contraindications, and Side Effects
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Safety in pregnant, lactating, or growing animals may not be fully established — consult a vet.
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Use with caution in animals with hepatic or renal impairment.
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Known allergy or hypersensitivity to ofloxacin, ornidazole, or members of fluoroquinolone / nitroimidazole classes is a contraindication.
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Possible side effects (based on class effects and similar drugs) may include gastrointestinal upset (vomiting, diarrhea), loss of appetite, nausea, or more rarely neurologic signs.
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Overdose risk: higher dosing can increase adverse effects; if overdose is suspected, seek immediate veterinary attention.
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Always ensure the full course is completed (unless directed otherwise) to prevent development of resistance.
Storage & Handling
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Store in a cool, dry, dark place (avoid heat, moisture, direct sunlight).
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Keep out of reach of children, other animals, or unintended access.
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Use within expiry date; do not use damaged or discolored tablets.
Packaging & Pricing
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The pack is often sold as 1 strip (10 tablets).
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Price (in India) is around ₹135 for the 10-tablet pack (some variation depending on seller)
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Some listings require a valid veterinary prescription.