Virbac Alizin (Aglepristone) 10ml for Canine Misalliance 

Alizin is a veterinary medicinal product containing aglepristone, a synthetic progesterone antagonist specifically developed for the treatment of canine misalliance. Aglepristone binds to uterine progesterone receptors with three times greater affinity than endogenous progesterone, effectively blocking the hormone essential for implantation and maintenance of pregnancy.

By competitively inhibiting progesterone, Alizin safely and reliably induces abortion in bitches when administered within the approved treatment window. It offers veterinarians a non-surgical, well-tolerated, and highly effective solution for the medical management of unwanted pregnancy in dogs.

Indications / Uses

Alizin is indicated for:

• Treatment of canine misalliance

• Medical termination of pregnancy in dogs

• Prevention of implantation after unintended mating

• Management of unwanted or accidental breeding

When Can Alizin Be Used?

• Authorised for use from Day 1 to Day 45 post-mating

• For optimal results, treatment is recommended after the end of oestrus (approximately 10–14 days post mating) to minimize the need for repeat courses

Dosage & Administration

• Dose: 10 mg/kg body weight

• Concentration: 30 mg/ml

• Administration: Subcutaneous injection

• Protocol: Two injections given 24 hours apart

• Volume: 1 ml per 3 kg body weight

• Maximum: 5 ml per injection site

(Timing and correct dosing are critical for treatment success.)

• Clinically proven aglepristone formulation

• High efficacy from 1 to 45 days post-mating

• Non-surgical alternative to pregnancy termination

• Blocks progesterone receptors to prevent pregnancy maintenance

• Two-dose protocol ensures reliable treatment outcome

• Excellent safety profile and well tolerated

• Flexible treatment window for veterinary convenience

• Simple subcutaneous administration

• Predictable and controlled pregnancy termination

•  Avoids risks associated with surgical intervention

• Suitable for early and mid-stage unintended pregnancy

• Supports responsible reproductive management

• Trusted solution for canine reproductive health