Powerful injectable antiemetic for dogs and cats This injectable formulation contains Ondansetron (2 mg/mL) and is used under direct veterinary supervision for rapid control of severe nausea and vomiting. It is especially beneficial in emergency settings or when oral dosing is impractical.
Composition
Ondansetron Hydrochloride – 2 mg/mL, in a 10 ml vial (Total active content: 20 mg of Ondansetron)
Indications / Uses
Primarily used for:
Control of vomiting due to chemotherapy
Severe or refractory vomiting when oral medications can't be tolerated
As part of supportive care in gastrointestinal disease, vestibular disorders, or toxin exposure
Premedication to prevent anesthesia-related nausea under veterinary guidance
Pharmacology & Onset
Belongs to the class of 5-HT₃ serotonin receptor antagonists, blocking signals from the gastrointestinal tract and brain’s vomiting centers.
Effects typically manifest within 1–2 hours, offering rapid relief.
Dosage & Administration
Administered only by a veterinarian—either intravenously (IV), intramuscularly (IM), or subcutaneously (SC)—based on the patient's condition.
Standard IV dosage ranges from 0.1–0.5 mg/kg every 8–12 hours, adjusted per clinical response.
Safety & Side Effects
Generally well tolerated in pets.
Potential side effects include:
Drowsiness, sedation
Constipation or mild gastrointestinal upset
Head shaking
Rarely, arrhythmias, hypotension, or neurological signs in overdose
Use with caution in pets with known sensitivity to ondansetron, liver impairment, or concurrent medications with pro-arrhythmic potential.
Always monitor patient response and adjust dosage as needed.
Storage
Store between 2 °C and 25 °C (36–77 °F).
Protect the vial from light and maintain sterility.
Directions for Use
Strictly for veterinary use; not for at-home administration.
Use aseptic technique for administration as per the treating veterinarian’s protocol.
Monitor for clinical improvement and any adverse reactions.